Selleckchem/HC-067047/S6637型
商品编号：
S6637
市场价：
¥17140.00
美元价：
10284.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | HC-067047 is a selective TRPV4 channel antagonist with IC50 values of 48 nM,133 nM,and 17 nM for human, rat, and mouse TRPV4 orthologs,respectively. | ||||||
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| Targets |
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| In vivo | HC-067047 causes a significant increase in functional bladder capacity in mice and rats suffering from cystitis, thus providing proof of principle that pharmacological inhibition of TRPV4 can be used to treat bladder dysfunction.HC-067047 had no effect on the cystometric parameters of Trpv4−/− mice demonstrates that the observed in vivo effects are specific.[1] |
品牌介绍
Selleck Chemicals是世界领先的高性能的生命科学产品供应商之一，主要致力于提供MAPK和PI3K/Akt/mTOR等上百个信号通路的高特异性小分子抑制剂。Selleck 产品线补充非常及时，可以提供行业内最新的抑制剂类产品。同时Selleck也是专业的高通量筛选抑制剂分子库、API、天然产物和多肽供应商。
